Friday, September 23, 2016

Cell Cycle MCQs part 4

Cell Cycle MCQs part 4
1. In order for anaphase to begin, which of the following must occur?
  • Chromatids must lose their kinetochores
  • Cohesin must attach the sister chromatids to each other
  • Cohesin must be cleaved enzymatically
  • Kinetochores must attach to the metaphase plate.
2. Why do chromosomes coil during mitosis?
  • to increase their potential energy
  • to allow the chromosomes to move without becoming entangled and breaking
  • to allow the chromosomes to fit within the nuclear envelope
  • to allow the sister chromatids to remain attached
The following applies to the questions below.

"Several organisms, primarily Protists, have what are called intermediate mitotic organization."

3. These Protists are intermediate in what sense?
  • They reproduce by binary fission in their early stages of development and by mitosis when they are mature
  • They never coil up their chromosomes when they are dividing
  • They use mitotic division but only have circular chromosomes
  • They maintain a nuclear envelope during division
4. What is the most probable hypothesis about these intermediate forms of cell division?
  • They represent a form of cell reproduction which must have evolved completely separately from those of other organisms
  • They demonstrate that these species are not closely related to any of the other Protists and may well be a different Kingdom
  • They rely on totally different proteins for the processes they undergo
  • They show some of the evolutionary steps toward complete mitosis but not all
5.Which of the following best describes how chromosomes move toward the poles of the spindle during mitosis?
  • The chromosomes are ʺreeled inʺ by the contraction of spindle microtubules
  • Motor proteins of the kinetochores move the chromosomes along the spindle microtubules
  • Non-kinetochore spindle fibers serve to push chromosomes in the direction of the poles
  • both A and B
6. Which of the following is a function of those spindle microtubules that do not attach to kinetochores?
  • maintaining an appropriate spacing among the moving chromosomes
  • producing a cleavage furrow when telophase is complete
  • providing the ATP needed by the fibers attached to kinetochores
  • maintaining the region of overlap of fibers in the cellʹs center

Use the following to answer the questions below.

"Nucleotides can be radiolabeled before they are incorporated into newly forming DNA and can therefore be assayed to track their incorporation. In a set of experiments, a student-faculty research team used labeled T nucleotides and introduced these into the culture of dividing human cells at specific times."

7. Which of the following questions might be answered by such a method?
  • How many cells are produced by the culture per hour?
  • What is the length of the S phase of the cell cycle?
  • When is the S chromosome synthesized?
  • How many picograms of DNA are made per cell cycle?
8. The research team used the setup to study the incorporation of labeled nucleotides into a culture of lymphocytes and found that the lymphocytes incorporated the labeled nucleotide at a significantly higher level after a pathogen was introduced into the culture. They concluded that
  • the presence of the pathogen made the experiment too contaminated to trust the results
  • their tissue culture methods needed to be relearned
  • infection causes lymphocytes to divide more rapidly
  • infection causes cell cultures in general to reproduce more rapidly
9. If mammalian cells receive a go-ahead signal at the G1 checkpoint, they will
  • move directly into telophase
  • complete the cycle and divide
  • exit the cycle and switch to a nondividing state
  • show a drop in MPF concentration
10. Cells that are in a nondividing state are in which phase?
  • G0
  • G2
  • G1
  • S
Cell Cycle MCQs
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Cell Cycle MCQs Parts =>

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